1,3-di-4-piperidylpropane derivatives as potential acetyl cholinesterase antagonists: Molecular docking, synthesis, and biological evaluation

Ahsaan Ahmed; Shamim Akhtar; Nousheen Mushtaq; Shazia Haider; Rabya Munawar; Hassaan Ahmed Siddique; Arifa Akram; Zafar Saeed Saify; Muhammad Arif

doi:10.36721/PJPS.2021.34.3.REG.855-860.1

original articles

1,3-di-4-piperidylpropane derivatives as potential acetyl cholinesterase antagonists: Molecular docking, synthesis, and biological evaluation

Ahsaan Ahmed, Shamim Akhtar, Nousheen Mushtaq, Shazia Haider, Rabya Munawar, Hassaan Ahmed Siddique, Arifa Akram, Zafar Saeed Saify, Muhammad Arif

Vol. 34

Issue 3

Pages 855-860

Online Date: 01 May 2021

Published: 01 May 2021

DOI: 10.36721/PJPS.2021.34.3.REG.855-860.1

Authors Abstract Related

Authors & Affiliations

Ahsaan Ahmed

Shamim Akhtar

Nousheen Mushtaq

Shazia Haider

Rabya Munawar

Hassaan Ahmed Siddique

Arifa Akram

Zafar Saeed Saify

Muhammad Arif

Abstract

Acetylcholine esterase (AChE) is a key biological target responsible for the management of cholinergic transmission

Keywords

Acetylcholine esterase (AChE)

Alzheimer’s disease (AD)

molecular docking

Piperidine

MOE (molecular orbital environment)

Ellman’s activity

Metrics

PlumX Metrics

original articles

1,3-di-4-piperidylpropane derivatives as potential acetyl cholinesterase antagonists: Molecular docking, synthesis, and biological evaluation

Ahsaan Ahmed, Shamim Akhtar, Nousheen Mushtaq, Shazia Haider, Rabya Munawar, Hassaan Ahmed Siddique, Arifa Akram, Zafar Saeed Saify, Muhammad Arif

Vol. 34

Issue 3

Pages 855-860

Online Date: 01 May 2021

Published: 01 May 2021

DOI: 10.36721/PJPS.2021.34.3.REG.855-860.1

Authors Abstract Related

Authors & Affiliations

Ahsaan Ahmed

Shamim Akhtar

Nousheen Mushtaq

Shazia Haider

Rabya Munawar

Hassaan Ahmed Siddique

Arifa Akram

Zafar Saeed Saify

Muhammad Arif

Abstract

Acetylcholine esterase (AChE) is a key biological target responsible for the management of cholinergic transmission

Keywords

Acetylcholine esterase (AChE)

Alzheimer’s disease (AD)

molecular docking

Piperidine

MOE (molecular orbital environment)

Ellman’s activity

Metrics

PlumX Metrics

1,3-di-4-piperidylpropane derivatives as potential acetyl cholinesterase antagonists: Molecular docking, synthesis, and biological evaluation

Authors & Affiliations

Abstract

Keywords

Metrics

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1,3-di-4-piperidylpropane derivatives as potential acetyl cholinesterase antagonists: Molecular docking, synthesis, and biological evaluation

Authors & Affiliations

Abstract

Keywords

Metrics