New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship

Rubina Siddiqui; Shamim Akhtar; Shazia Haider; Zafar Saied Saify; Mahwish Akhtar; Sana Shamim

doi:10.36721/PJPS.2021.34.4.REG.1415-1420.1

original articles

New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship

Rubina Siddiqui, Shamim Akhtar, Shazia Haider, Zafar Saied Saify, Mahwish Akhtar, Sana Shamim

Vol. 34

Issue 4

Pages 1415-1420

Published 01 Jul 2021

DOI: 10.36721/PJPS.2021.34.4.REG.1415-1420.1

Authors Abstract Related

Authors & Affiliations

Rubina Siddiqui

Shamim Akhtar

Shazia Haider

Zafar Saied Saify

Mahwish Akhtar

Sana Shamim

Abstract

Seven new hydrazinyl thiazole derivatives of piperidin-4-one (PE3-PE9) have been synthesized by cyclization of intermediate thiosemicarbazone derivative (PE2).

Keywords

Piperidin-4-one

hydrazinyl thiazole derivatives

analgesic activity

tail flick method

Metrics

PlumX Metrics

original articles

New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship

Rubina Siddiqui, Shamim Akhtar, Shazia Haider, Zafar Saied Saify, Mahwish Akhtar, Sana Shamim

Vol. 34

Issue 4

Pages 1415-1420

Published 01 Jul 2021

DOI: 10.36721/PJPS.2021.34.4.REG.1415-1420.1

Authors Abstract Related

Authors & Affiliations

Rubina Siddiqui

Shamim Akhtar

Shazia Haider

Zafar Saied Saify

Mahwish Akhtar

Sana Shamim

Abstract

Seven new hydrazinyl thiazole derivatives of piperidin-4-one (PE3-PE9) have been synthesized by cyclization of intermediate thiosemicarbazone derivative (PE2).

Keywords

Piperidin-4-one

hydrazinyl thiazole derivatives

analgesic activity

tail flick method

Metrics

PlumX Metrics

New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship

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Abstract

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New series of hydrazinyl thiazole derivatives of piperidin-4-one: Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship

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Abstract

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