By: Xiaojuan Guo, Yan Chen, Wei Jiang, Xingfeng Yu, Qinhu Zhang, Hui Li, Qianfeng He
Keywords: Incontinence-associated dermatitis; Inflammatory responses; Longgu; Nutritional status; Safety
DOI : 10.36721/PJPS.2025.38.6.REG.13082.1
Abstract: Incontinence-associated dermatitis (IAD) is a progressive disease based on the occurrence of incontinence. Longgu is a very classic Chinese medicine, which can promote blood coagulation and reduce vascular permeability. In this study, we analyzed the therapeutic effect of Longgu on IAD. We divided 102 patients with IAD into a control group using routine treatment and an experimental group using Longgu treatment to compare their wound healing time and clinical outcomes. In addition, the levels of inflammatory response and nutrient proteins were examined before and after treatment in both groups. Finally, a 6-month follow-up investigation was conducted to record the mortality rate and IAD recurrence rate of the patients. The results showed that the experimental group had a shorter wound healing time and better efficacy (P<0.05). Inflammatory factors were lower and nutritional proteins were higher in the experimental group than in the control group after treatment (P<0.05). In addition, the prognostic overall survival rate of the experimental group was higher than that of the control group (P<0.05). This shows that Longgu is an excellent IAD treatment program.
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