Pharmacokinetics and tissue distribution study of two novel quinazoline PI3K/mTOR dual-inhibitors, potential anticancer agents Page No: 1527-1542

By: Jiangang Chen, Xiaoli Bian, Sanqi Zhang, Guangde Yang

Keywords: Quinazoline derivative, pharmacokinetics, tissue distribution, anticancer, HPLC

DOI : 10.36721/PJPS.2023.36.5.REG.1527-1542.1

Abstract: S1 and S2, two structurally similar quinazoline derivatives, are novel anticancer drugs targeting the PI3K/AKT/mTOR signaling pathway channel

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