Pharmacokinetic study of granisetron in human plasma measured by UPLC-MS/MS and its use in healthy Chinese subjects
Page No: 475-489
By: Lingying Jiang, Lei Mao, Jie Lin, Jiangmin Cheng, Zebei Liu, Hangyu Zhao, Xin Zhang, Chenfang Wang, Linfang Deng
Keywords: Granisetron, UPLC-MS, validation, pharmacokinetic
DOI : 10.36721/PJPS.2024.37.3.REG.475-489.1
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By: Lingying Jiang, Lei Mao, Jie Lin, Jiangmin Cheng, Zebei Liu, Hangyu Zhao, Xin Zhang, Chenfang Wang, Linfang Deng
Keywords: Granisetron, UPLC-MS, validation, pharmacokinetic
DOI : 10.36721/PJPS.2024.37.3.REG.475-489.1
Abstract: In this study, a rapid, simple and sensitive UPLC-MS/MS method was established for the quantification of granisetron in human plasma for the prevention of vomiting after radiotherapy and chemotherapy
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