Assessment of the impact of combining butylphthalide and atorvastatin on neurological function, quality of life and vascular endothelial function in individuals diagnosed with acute cerebral infarction Page No: 1003-1010

By: Zhixuan Wu, Maojuan Wang, Quanxi Mao, Ying Li, Zuoxiao Li

Keywords: Acute cerebral infarction, butylphthalide, atorvastatin, vascular endothelial function, neurological function, quality of life.

DOI : 10.36721/PJPS.2024.37.5.REG.1003-1010.1

Abstract: Acute cerebral infarction poses a significant health risk and effective treatment is crucial. This randomized controlled trial assessed the impact of combining Butylphthalide and Atorvastatin on neurological function, quality of life and vascular endothelial function in 124 individuals with acute cerebral infarction. Participants were randomized into control and experimental groups, with the latter receiving the combination therapy. Objective assessments using NIHSS, SS-QOL, MBI and MoCA scales, along with biochemical markers, demonstrated improved outcomes in the experimental group. This study provides evidence for the clinical benefits of the drug combination in managing acute cerebral infarction.



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