By: Xiaoyu Lan, Hongyan Sun, Kun Shi, Xiaohong Sun, Taoran Wang, Hui Wang
Keywords: Postmenopausal osteoporosis, caltrate D, eight section brocade, bone metabolism, bone formation.
DOI : 10.36721/PJPS.2024.38.1.REG.001-006.1
Abstract: Caltrate D is a commonly used drug in the treatment of postmenopausal osteoporosis (PMOP), but the effect of single application is not ideal. Therefore, to investigate the eight section brocade therapy combined with caltrate D effect in preventing and treating PMOP. From January 2021 to June 2022, 110 postmenopausal women with decreased bone mass were selected and randomized into group A (n = 54) and group B (n = 56). The both group receiving caltrate D treatment, and group B added receiving Chinese medicine eight section brocade therapy. Bone mineral density (BMD), WHOQOL-BREF score and incidence of PMOP were compared in both groups. The bone metabolism indexes [serum calcium, phosphorus, alkaline phosphatase (ALP)], bone formation indexes [serum Procollagen I N-Terminal Propeptide (PINP), type 1 collagen C-terminal cross-linked telopeptides (?-CTX)] were detected in both groups. After treatment, lumbar BMD, femoral neck BMD, serum calcium level and WHOQOL-BREF score in group B were significantly higher compared to group A, serum phosphorus and ALP levels, PMOP recurrence rate decreased significantly, and no significant difference in serum PINP and ?-CTX levels in both groups. This combination therapy is significantly effective and provides a new reference for the clinical treatment of PMOP.
[View Complete Article]
