By: Yinfang Li, Xia Kong, Dan Xu, Peiling Yin
Keywords: Budesonide, mycoplasma pneumoniae pneumonia, vitamin C, immunoglobulin
DOI : 10.36721/PJPS.2025.38.3.REG.13416.1
Abstract: To observe the therapeutic effect of vitamin C combined with budesonide (BUD) on Mycoplasma pneumoniae (MP) pneumonia. A total of 106 children with MP admitted to our hospital from June 2021 to December 2024 were selected for the study. 57 children received vitamin C combined with conventional treatment (control group); the other 49 children were treated with vitamin C combined with BUD treatment (research group). The clinical efficacy of the two groups was compared and the time of disappearance of fever, cough and pulmonary wet rales was counted. Lung function, inflammatory factor and immunoglobulin levels were measured before and after treatment and adverse reactions were recorded. The results showed that the total effective rate of treatment in the study group was higher than that in the control group, while the time of fever, cough and disappearance of pulmonary wet rales was shorter than that in the control group (P<0.05). After treatment, the lung function of the study group was significantly better than that of the control group, while the level of inflammatory factors was lower than that of the control group (P<0.05). In addition, Immunoglobulins (Ig)A and IgM decreased and IgG increased in both groups after treatment, with the difference in the study group being more significant (P<0.05). Comparison of the incidence of adverse reactions between the two groups, on the other hand, showed no significant difference (P>0.05). These results suggest that the combination of vitamin C and budesonide may be of great value in the future treatment of MP pneumonia.
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